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Remeron is an antidepressant, which is an antagonist of presynaptic a2-adrenergic receptors in the central nervous system. Synonyms are Mirtazapine, Mirzaten, Mirtazonal, Noxibel, Esprital. Remeron is a fast, powerful, stable antidepressant drug of first choice, which is used for short-term and long-term treatment of depression. The drug is most effective when the clinical manifestation of depression symptoms such as inability to get pleasure (anhedonia), psychomotor retardation, sleep disorders, and other symptoms of depression, such as loss of interest in life, suicidal thoughts and mood swings (better in the evening than in the morning). Purchase non-prescription Remeron online in our pharmacy.

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Remeron is an antidepressant, blocks the pre-synaptic alpha 2-adrenergic in the central nervous system and increases the noradrenergic transmission of nerve impulses, also enhances serotonin transmission (if this effect is realized only through the 5-НТ1-receptors, since the 5-HT2 and 5-НТ3-receptors are blocked).

We offer you to order cheap Remeron online no Rx. After intake the drug is absorbed rapidly, bioavailability is about 50%; the maximum concentration in the blood is achieved in approximately 2 hours, tying with the plasma protein - about 86%. Equilibrium concentration in the blood is achieved after 3-4 days of admission. In the recommended dose range pharmacokinetic parameters have a linear dependence on the dose. The drug is actively metabolized in the liver by demethylation and oxidation with followed conjugation. The original active substance is excreted with the urine and faeces, T1/2 is 20-40 hours, sometimes - up to 65 hours (which allows you to take it 1 time per day), T1/2 in young people is shorter than in the elderly. Clearance may decrease in renal or hepatic insufficiency.

In pregnancy the application is possible only in case of extreme necessity (the safety of the pregnant women has not been studied). At the time of treatment you should stop breastfeeding (no data on the penetration in milk).

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